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| Center/Lab | Discipline | Research Class | Head Chair |
|---|---|---|---|
| Building Engineering Group | Civil/Environmental Engineering | INCOLL | John Straube |
| Canadian Cold Formed Steel Research Group | Civil/Environmental Engineering | INCOLL | Reinhold Schuster |
| Centre for Advanced Materials Joining (CAMJ) | Mechanical Engineering | INDEPT | Norman Zhou |
| Centre for Advanced Photovoltaic Devices and Systems | Electrical Engineering | INCOLL | Siva Sivoththaman |
| Centre for Advancement of Trenchless Technologies (CATT) | Civil Engineering | INDEPT | Mark Knight |
| Centre for Bioengineering and Biotechnology (CBB) | Biomedical Engineering | INUNIV | Catherine Burns |
| Centre For Business Entrepreneurship Technology | Engineering Management | INCOLL | Rod McNaughton |
| Centre for Integrated RF Engineering | Electrical Engineering | INCOLL | Raafat Mansour |
| Centre for Intelligent Antenna and Radio Systems | Electrical/Computer Engineering | INCOLL | Safieddin Safavi-Naeini |
| Centre for Pattern Analysis & Machine Intelligence (CPAMI) | Electrical Engineering | INDEPT | Mohamed Kamel |
| Centre for Pavement and Transportation Technology (CPATT) | Civil/Environmental Engineering | INDEPT | Susan Tighe |
| Centre for Wireless Communications | Electrical Engineering | INCOLL | Sherman Shen |
| Conflict Analysis Group | Other Engineering Disciplines | INCOLL | Keith Hipel |
| Control Systems Group | Electrical Engineering | INDEPT | Chris Nielsen |
| Environmental Modelling and Analysis Group | Civil/Environmental Engineering | INDEPT | James Craig |
| Fire Research Group | Mechanical Engineering | INUNIV | Beth Weckman |
| Giga to Nanoelectronics Centre | Electrical/Computer Engineering | INCOLL | William Wong |
| Hyper Connectivity Lab | Electrical Engineering | INDEPT | Amir Khandani |
| Institute for Computer Research | Computer Engineering | INUNIV | Vic DiCiccio |
| Institute for Innovation Research | Engineering Management | INUNIV | Paul Guild |
| Institute for Polymer Research | Chemical Engineering | INUNIV | Alex Penlidis |
| Mechatronics | Mechanical Engineering | INCOLL | Sanjeev Bedi |
| Medical Instrument Analysis and Machine Intelligence Group (MIAMI) | Electrical Engineering | INCOLL | Magdy Salama |
| Multimedia Communications Lab | Electrical Engineering | INDEPT | En-Hui Yang |
| NSERC Cell Factory Bioprocessing Research Network (CellNet) | Chemical Engineering | INUNIV | Murray Moo-Young |
| Power and Energy Systems Group | Electrical Engineering | INDEPT | Shesha Jayaram |
| RF Microwave and Photonics Group | Electrical Engineering | INDEPT | Ali Safavi-Naeini |
| Software Engineering Group | Computer Engineering | INCOLL | Ladan Tahvildari |
| Transportation Systems Research Group | Civil/Environmental Engineering | INUNIV | Liping Fu |
| Tribology Research Group | Mechanical Engineering | INCOLL | John Medley |
| Uncertainty Management Laboratory | Engineering Management | INCOLL | Frank Safayeni |
| Usability and Interactive Technology Lab | Other Engineering Disciplines | INDEPT | Carolyn MacGregor |
| Vision and Image Processing Group | Other Engineering Disciplines | INDEPT | Fakhri Karray |
| VLSI Group | Electrical Engineering | INDEPT | David Nairn |
| Waterloo Centre for Automotive Research (WATCar) | Mechanical Engineering | INUNIV | Amir Khajepour |
| Waterloo Formal Methods | Electrical Engineering | INUNIV | Mark Aagaard |
| Waterloo Hydrology Lab | Civil/Environmental Engineering | INDEPT | Eric Soulis |
| Waterloo Institute Sustainable Energy | Civil/Environmental Engineering | INUNIV | Jatin Nathwani |
| Waterloo Management of Integrated Manufacturing Systems Research Group | Engineering Management | INCOLL | James Bookbinder |