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| Center/Lab | Discipline | Research Class | Head Chair |
|---|---|---|---|
| Advanced Radar Research Center (ARRC) | Electrical/Computer Engineering | INUNIV | Robert Palmer |
| Biocorrosion Center | Civil/Environmental Engineering | INUNIV | Joseph Suflita |
| Carbon Nanotube Technology Center (CaNTeC) | Chemical Engineering | INCOLL | Daniel Resasco |
| Center for Biomass Refining (CBR) | Chemical Engineering | INCOLL | Lance Lobban |
| Center for Intelligent Transporations Systems | Electrical/Computer Engineering | INCOLL | Joseph Havlicek |
| Center for Interfacial Reaction Engineering (CIRE) | Chemical Engineering | OUTUNIV | Daniel Resasco |
| Center for Restoration of Ecosystems and Watersheds (CREW) | Civil/Environmental Engineering | INCOLL | Robert Nairn |
| Center for Symbiotic Research | Computer Science (inside engineering) | INCOLL | Andrew Fagg |
| Center for the Study of Wireless Electromagnetic Compatibility (EMC) | Industrial/Manufacturing/Systems Engineering | INCOLL | Floyd Grant |
| Dynamic Structures Sensing & Control Center (DySSC) | Mechanical Engineering | INCOLL | David Baldwin |
| Institute for Applied Surfactant Research (IASR) | Chemical Engineering | INUNIV | Brian Grady |
| Institute for Biomedical Engineering, Science, and Technology (IBEST) | Biomedical Engineering | INCOLL | Hong Liu |
| Integrated Core Characterization Center (IC3) | Petroleum Engineering | INUNIV | Chandra Rai |
| Integrated PoroMechanics Institute (iPMI) | Petroleum Engineering | INUNIV | Younane Abousleiman |
| Research Institute for STEM Education (RISE) | Engineering (General) | INUNIV | Susan Walden |
| Risk-Based Systems Analysis Laboratory | Industrial/Manufacturing/Systems Engineering | INCOLL | Kash Barker |
| Sooner Engineering Education Center (SEED) | Other Engineering Disciplines | INUNIV | Randa Shehab |
| Southern Plains Transportation Center (SPTC) | Engineering (General) | INUNIV | Musharraf Zaman |
| Water Technologies for Emerging Regions (WaTER) Center | Civil/Environmental Engineering | INCOLL | David Sabatini |
| Wireless and Electromagnetic Compliance and Design Center (WECAD) | Electrical/Computer Engineering | INCOLL | Hazem Refai |