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Indiana University-Purdue University Indianapolis - 2016

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Research Description

Research Description By Graduate Engineering Department

Biomedical Engineering (BME)

The research activities of the biomedical engineering department are in the following areas:

1) Advanced Biomedical Polymer Sciences
2) Biomechanics and Biomaterials
3) Biomedical Instrumentation
4) Biomolecular Engineering
5) Biosignal Processing
6) Cardiovascular Engineering
7) Cellular and Molecular Bioengineering
8) Neural Engineering
9) Neuroelectrophysiology and Computational Neurosciences
10) Orthopedic Research

Electrical and Computer Engineering (ECE)

The research activities of the electrical and computer engineering department are in the following areas:

1) Automatic, Control, and Power Systems
2) Circuits & Systems
3) Computer Communication Network
4) Computer Engineering and Systems
5) Data Analysis
6) Digital Signal Processing, Image Processing, and Communications
7) Electric Power Systems
8) Information Security
9) Intelligent Transportation and Active Safety Systems
10) Medical Imaging
11) Micro- and Nano-Electronics and VLSI Design
12) Multimedia
13) Parallel Programming
14) Pattern Recognition
15) Power Electronics
16) Software Engineering

Mechanical Engineering (ME)

The research activities of the mechanical engineering department are in the following areas:

1) Additive Manufacturing
2) Advanced and Renewable Energy Research
3) Advanced Manufacturing
4) Advanced Materials
5) Biomechanics
6) Combustion and Propulsion
7) Computational Engineering (computational fluid dynamics, computational solid dynamics, and computational materials)
8) Energy Efficiency
9) Mechatronics and Automotive Control
10) Molecular Kinetics
11) Nanotechnologies

Research Description By Engineering Research Center

Advanced Manufacturing Laboratory

The Advanced Engineering and Manufacturing Laboratory (AEML) was established in 1998 to facilitate teaching and research in the areas of CAD (Computer Aided Design), CAE (Computer Aided Engineering), CAM (Computer Aided Manufacturing), IPS (Interactive Product Simulation), and PDM (Product Data Management).

It creates a base to train high-tech and advanced manufacturing workforces to meet the needs of the rapid changing technology and provide service to industry for promoting the new technology.

Advanced Materials Laboratory

Comprehensive materials processing, characterization, and computational resources are available at IUPUI for materials-based research projects. Researchers have access to equipment and instrumentation for advanced materials' fabrication and characterization. AML (~900 sq. ft.) has equipment in the lab or from shared facilities.
(a) Modeling and Simulation Software Packages: Materials Studio (from Accelrys), LAMMPS (Large-scale Atomic/Molecular Massively Parallel Simulator), Comsol Multiphysics, Vienna Ab-initio Simulation Package (VASP), and ANSYS Finite Element Software.
(b) Materials Processing and Characterization Equipment: MTS 1123 Universal Testing Machine, Microhardness tester (M-400, Leco Co., St. Joseph, MI), Tube Furnace (GSL-1600X, MTI Corp., Richmond, CA), Universal Testing Machine (Sintech Renew 1121, Instron Engineering Corp., Canton, MA), Bench-top Planetary Automatic Ball Mills with 4 Alumina Jars, EQ-SFM-1 (MTI), Leco VP-150 Polishing Machine, Nikon UM-2 Optical Microscope, and Leco Metallograph and Optical Microscope with Digital Imaging Capabilities.
(c) Additive Manufacturing 3D Printers: Two customized ceramic printers for alumina, Zirconia, and carbide. Plastic printers; two HE3D i3 dual-nozzle plastic printers; Stratasys Dimension SST plastic printer

Advanced Power Electronics Laboratory

The mission of the Advanced Power Electronics Laboratory at IUPUI is to develop electronic solutions for systems dealing with energy conversion, focusing on efficiency, power quality, reliability, and cost.
Post-docs, PhD, and Master Science students develop research in the following sub-areas: Renewable Energy, Energy Efficiency, Power Converters, Fault Tolerant Systems, and Active Power Filters.

Battery Material and Testing Laboratory

The Battery Materials and Testing Lab was established in 2010 and has facilities for manufacturing and testing battery materials for next generation lithium ion batteries with a higher energy density, lower cost, and better safety. The research activities include the development of novel battery chemistries, such as Li/air, Li/sulfur, and Na/ion cells and characterization of high capacity anode materials, such as silicon, tin, and germanium.

Bioelectronics Laboratory

The bioelectric phenomenon is the basic mechanism by which the body communicates and processes information through the substrate of the nervous system. These signals impact how the body functions including modulation and control of major organ systems including the cardiac, pulmonary, renal, endocrine, reproductive, motor, and sensory systems. The Bioelectronics Lab aims to develop devices to manipulate and interface to organs that take advantage of the bioelectric phenomenon to 1) develop novel devices, therapies, and sensing modalities, 2) understand how these internal organ systems control and modulate themselves in the normal and pathological cases, 3) develop bioelectronically-based therapies and interventions, and 4) translate these devices and interventions through to clinical and scientific use. The laboratory investigates how neuroprosthetic devices interact with bioelectric tissues through first hand measurement to develop in-silico biophysical models and tools that enable the creation and design of novel devices, diagnostic methods, and therapies.

Biomechanics and Biomaterials Reseach Center

Biomechanics and Biomaterials Research Center is one of the signature centers of IUPUI, where the following research is performed:
1. Mechanobiology
2. Tissue Engineering
3. Biomaterials

Biomedical Polymer Materials Laboratory

1) Development of advanced biomaterials for dental restoratives and orthopedics biological properties
2) Development of biodegradable polymers for tissue engineering
3) Development of functional polymers for improved tissue and organ transplantations

Bone Biology and Mechanics Laboratory

The BBML utilizes multiscale approaches to investigate composition, architecture, mechanical integrity and fracture resistance at discrete length scales throughout the hierarchy of bone in the context of:
1. Skeletal disease states
2. Following external mechanical stimulation
3. With pharmacological treatment
The goal of the lab is to understand how biological and environmental factors influence the assembly and organization of bone with an eye toward the development of rational approaches for the diagnosis and treatment of defects, damage and disease in this important organ system.

Cardiovascular Neurophysiology Neurobiology Laboratory

1) Computational Neuroscience
2) Sensory neuron and synapse electrophysiology
2) Neural coding in cardiovascular afferents
3) Patch clamp instrumentation

Cell Mechanics/Mechanotransduction Laboratory

The primary objective of our research group is to understand the biophysical mechanism by which cells sense and respond to specific physical stimuli in the environment, including dimensionality and rigidity of the extracellular matrix as well as mechanical force. As recent technology advances explosively in areas such as computing, molecular biology, nanotechnology, and microscopy, it is becoming increasingly recognized that the fundamental question of how cells function cannot be solved by focusing exclusively on individual genes and proteins; it also depends on mechanical cues, local microenvironment, and system level integration, which has collectively led to the fascinating new field: Mechanotransduction.

Center for Additive Manufacturing Research

The Center for Additive Manufacturing Research at IUPUI (CAMRI) was established in 2016 to serve as an umbrella and a vehicle for additive manufacturing research, education, and service activities at IUPUI, which is currently a silver member of the National Additive Manufacturing Innovation Institute (America Makes). The affiliated labs and centers are involved in a wide range of research and educational activities that span several technology focus areas of additive manufacturing including design (optimization, design computational tools), materials (modeling and characterization), process (intelligent machines, online monitoring and control and physics-based modeling), and product lifecycle (digital thread).

Center for Biomechanics and Biomaterials

Center for Biomechanics and Biomaterials is one of the signature centers of IUPUI, where the following research is performed:

1) Cardiovascular and Gastro-intestinal Biomechanics
2) Coronary Circulation in Health and Disease
3) Tissue Engineering
4) Diagnostic and Therapeutic Devices
5) Mechanobiology
6) Skeletal Biomechanics

Combustion and Propulsion Research Laboratory (CPRL)

The Combustion and Propulsion Research Laboratory (CPRL) at IUPUI was established to advance novel technologies and modern sciences to support clean, safe, and efficient combustion processes. Innovative combustion technologies are being investigated for novel engines with remarkably low energy consumption and environmental impact, and for avoiding fire disasters in spacecraft and buildings. Sophisticated optical diagnostic methods and high-fidelity computational methods are applied to fascinating and potentially useful unsteady combustion and inverse flame behavior.

Computational Fluid Dynamics Laboratory

The Computational Fluid Dynamics Laboratory was established in 1986 within the Department of Mechanical Engineering to conduct research and develop software in the areas of computational fluid dynamics and heat transfer. Current emphasis is on the following areas: High performance scientific computing; Parallel and Grid computing; Multiscale modeling.

D2KD - Data Driven Knowledge Discovery

The Data Driven Knowledge Discovery Laboratory focuses on developing information systems and algorithms that are inspired by data and patterns in the data. Students affiliated with the lab work on various projects including digital clones, data analytics, and social computing. Each of these topics can be addressed in various application domains with a current focus on health and supply chain visibility.

Driving Simulator Laboratory

The Transportation Active Safety Institute (TASI) has established a driving simulator laboratory for research into driver behavior and for testing active-safety system performance. The Drive Safety DS-600c Driving Simulator provides a flexible and realistic environment for testing. The DS-600c joins a more basic STISIM WT-2000 Driving Simulator and a sophisticated Compumedics system that provides a comprehensive capability to acquire biomedical data including ECG, EMG, EEG, etc. Use of these TASI facilities will be available to TASI members at reduced hourly rates.

Electronic and Electrochemical Materials and Devices Laboratory

The Electronic and Electrochemical Materials and Devices Laboratory (EEMDL) was established in November 2007. The major research directions are 1) polymer electrolyte membrane fuel cells (PEMFCs) including the high performance and durable Pt and Pt alloy nano-particle catalysts, graphene-based catalyst supports, and advanced membrane electrode assembly (MEA) with high performance, long durability, and low cost, 2) advanced batteries including the anode (i.e., Li metal electrode, PANI-Si-Graphene composite, SnO2), cathode (LiFePO4, V2O5/Graphene composite, FeOF and CuF2, etc.), additives, separator (Thermoplastic Polyurethane), electrolyte and battery safety, 3) nano-materials including nano-carbon particles, nano-graphic, and graphenes, etc., and 4) hydrogen production and storage including water electrolysis and physical absorption of hydrogen. Currently, extensive work focuses on the applications of graphenes on PEMFC, battery and water splitting. Most of the projects are/were supported by industry, National Science Foundation (NSF), and the Department of Energy. The EEMDL has more than $1.0 million equipment and instrument and has produced more than 40 journal publications and 13 patent applications so far with a total $3,386 million research funds.

Embedded Systems, DSP, and Mobile Laboratory

The Embedded Systems, DSP, and Mobile laboratory was established by grants and donations from Freescale, ARM, NXI, and Mentor Graphics. It includes the state of art embedded systems for embedded, sensors, Ethernet, wireless, and internet of things applications. It also includes Catapult C high level synthesis package for synthesizing pipelined, multi-block subsystems from untimed ANSI C/C++ descriptions. Catapult C's generate RTL (VHDL and Verilog) targeted to ASICs and FPGAs for speech, image, and video applications.

Energy Conversion Systems Laboratory

The mission of the Energy Conversion Systems Laboratory (ECS-Lab) is to develop electronic solutions for systems dealing with energy conversion, focusing on efficiency, power quality, reliability and effective cost.
The research activities of the ECS-Lab are the following:
1) Introduction of carbon-nanotubes to improve thermal performance on power electronics converters
2) Development of more efficient photovoltaic solar microinverters
3) Advanced topologies for applications in Uninterruptable Power Supply (UPS)
4) Integration of renewable energy systems to the grid

Engineering Design Research Laboratory

The IUPUI Engineering Design Research Laboratory (EDRL) was established in 2011 to advance simulation-based design methods for engineering systems, structures, and materials. The aim is to exploit and develop energies among structural engineering, engineering mechanics, material science, and manufacturing to introduce new insights and capabilities to engineering design. The long-term vision is to develop multidisciplinary, multiscale design methodologies to address challenges in the design of novel materials, products, and systems in a highly integrated manner. Fundamental research topics include structural topology optimization, design of multiscale and multimaterial systems, and design for additive manufacturing. Applications include vehicle structural optimization (e.g., crashworthiness and blast mitigation), helmets and sport gear design, composite material optimization and their integration in a multiscale material, and structure design methodology.

Industrial Assessment Center

The IUPUI Industrial Assessment Center is sponsored by the Department of Energy. It was established in September 2011 to train energy efficiency experts and conduct energy assessments to manufacturing companies. The purpose of Energy Savings Assessments is to identify immediate opportunities to save energy and to reduce cost, by focusing on key systems: steam, process heating, compressed air, fan, drives, lighting, and pumping systems. These processes consume most of the energy used by U.S. industry. Fine-tuning of these systems may cost little but offers the company the potential to yield large savings. Quick successes with optimizing these systems can lead to significant long-term savings if the approach is spread throughout the company's plants.

Initiative for Product Lifecycle Innovation

Established in 2014, with a research and education mission, the Initiative for Product Lifecycle Innovation (IPLI) is an IUPUI wide initiative that works with industry and other partners to advance and promote best practices pertaining to Product and Process Lifecycle, including PLM (Product Lifecycle Management), SE (Systems Engineering), Digital Manufacturing and Design, Advanced Engineering, and Sustainability. IPLI serves as a test bed and vehicle for the rapid implementation of advanced Product Lifecycle technologies in Advanced Manufacturing as well as life sciences industries.

Integrated Nanosystems Development Institute

The Integrated Nanosystems Development Institute (INDI) was established in 2009 bringing together the expertise and resources in nanoscale science and engineering at IUPUI, coupled with the desire by the IUPUI researchers from diverse disciplines to develop nanotechnology-based systems that address major societal and economic needs. The vision of INDI is to be a world-class resource for the realization of nanotechnology-based miniaturized systems that contribute to the economic growth and social advancement of Indiana and the nation and benefit humanity as a whole. The mission of INDI is 1) to enable, through Innovative interdisciplinary research and educational programs, the development of nanotechnology-based systems for biomedical, energy, environmental, information technology, and other applications, and 2) to provide solutions which through translation of research into practice and technology transfer, contribute to social wellbeing and economic growth.

Intelligent Vehicles Research Laboratory

Intelligent Vehicles Research Laboratory was established in 2011 to develop unique vehicle test equipment and conduct vehicle tests for active safety-related features. The research results are shared with government agencies and auto industry world wide. Interdisciplinary collaboration (such as computer engineering, mechanical engineering, computer science, human-factor engineering social science and medical fields) is essential for the research in this lab.

Mechatronics and Automotive Control Laboratory

The Mechatronics Research Laboratory (MRL) was established in 2005 to facilitate teaching and research in the areas of Mechatronics and Intelligent Systems, Diagnostics/Prognostics, Advanced Control Systems, Modeling and Simulation, Drive-By-Wire Systems, and Sensors & Algorithms. MRL is aimed at creating high-tech workforce in the area of mechatronics and intelligent systems by providing appropriate training to the students in order to meet the needs of these rapidly changing technologies and provide services to industry for promoting new technologies.

Molecular Kinetics Laboratory - Ion and Nanoparticle Characterization Facility

Ever wonder how explosives are detected at an airport detection system, how forensic analysts look ofr chemical "fingerprints" that point towards the culprit or how ion beams are the future of space propulsion? The Molecular Kinetics Lab, established in 2015, uses state of the art analytical techniques which are sensitive enough to detect, identify and quantitate molecules and nanoparticles in a medium based on their mass, charge, and/or size. These ionization and characterization technologies are employed in unique ways in medical, biomedical, forensic, pharmaceutical, propulsive, pollution impact, aerosol and particle technology and renewable energy industries.

Richard G. Lugar Center for Renewable Energy

The Richard G. Lugar Center for Renewable Energy is one of the Signature Centers of IUPUI. It was established in March 2007 to address the societal needs for clean, affordable and renewable energy sources, improve the nation's energy security, and reduce global warming. Its primary mission is to promote research excellence in the area of renewable energy through collaborative efforts among faculty in the disciplines of engineering, chemistry, physics, biology, and environmental affairs. It will promote renewable energy applications through teaching, learning, civic engagement, and synergistic partnerships with industry, government labs and local communities.

Skeletal Research Laboratory

Skeletal Research Laboratory was established in 1998 to train biomedical engineers and scientists, and conduct research in the area of skeletal mechanics and biology using multidisciplinary expertise such as biomechanics, bioinformatics, computer simulation, and molecular and cell biology.

Transportation Active Safety Institute

Transportation Active Safety Institute was established in 2006. It is a signature center at IUPUI. The following research is performed:
1) Crash and Naturalistic Driving data analysis
2) Automated driving and autonomous vehicles
3) Active safety systems testing and evaluation
4) Image processing and pedestrian/bicyclist recognition
5) Connected vehicles and V2X
6) Human factors in driving safety
7) Impaired and distracted driving
8) Modeling and simulation
9) Young and older driver behavior
10) Biomechanics in active safety systems
11) Vehicle dynamics and control

Vascular Mechanobiology Laboratory

The objective of the Vascular Mechanobiology Laboratoy is to understand the effect of mechanical forces in vascular cell physiology, in particular its impact on vascular aging. We are focused on molecular interactions at the cell nucleus, and force transduction at the nuclear lamina. Defects in nuclear lamina could lead to signs of aging and be involved in cell senescence. While normal mechanical and hemodynamic forces in the vasculature are necessary for maintaining homemstasis, they can also contribute to localized pathological conditions as well as the normal vascular aging. We use mechanical tools to simulate conditions in vitro, and molecular and cellular biology techniques and imaging tools to analyze changes in cell behavior and functions. These studies will lead to better understanding of mechanical forces in vascular aging and improved methods of treatment and prevention of vascular diseases.

Vehicle and Crash Data Analysis and Processing Laboratory

The National Highway Traffic Safety Administration (NHTSA) estimates ("The Economic Impact of Motor Crashes 2000" NHTSA, DOT HS-809-446, May 2002) the annual societal cost of motor vehicle crashes in the U.S. at $230.6 billion based on
* 6,328,000 reported crashes involving 11.3 million vehicles
* 4,365,000 crashes per year resulting in property damage
* 1,925,000 crashes resulting in injuries
* 38,252 crashes resulting in 42,643 fatalities

Over the last four decades, the numbers of injuries and fatalities per traveled mile have decreased significantly. However, over the last two decades these numbers have leveled off, indicating that new approaches will be needed in order to achieve additional reductions. Thus automotive suppliers have begun developing active safety products, whose goal is to prevent or mitigate crashes, as opposed to passive safety products, such as seat belts and air bags that provide protection only in a crash. An active safety system senses aspects of the vehicle, driver, traffic, and/or roadway to identify and assess impending crash events, then attempts to avoid the crash either by warning the driver or by taking appropriate control actions such as braking. Active safety products in development include adaptive cruise control, collision warning, lane-departure warning, and lane-keeping systems.

TASI will provide a collaborative environment, facilitating interaction among academic researchers, automotive supplies, vehicle manufacturers, and government regulatory agencies addressing vehicular active safety issues. Through the partners combined efforts, TASI activities will help bridge the gap between innovation, market launch, and evaluation of commercial products. This will speed the market introduction of active safety systems, thereby reducing crash-related injuries, loss of life, and property damage, while promoting innovative companies that boost Indiana's economy.