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University of Missouri - 2016

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Research Description

Research Description By Graduate Engineering Department


The Department of Bioengineering at the University of Missouri is a broad-based program that integrates faculty, education and research in the following areas:
- Biomedical engineering,
- Bioprocess engineering, and
- Bioenvironmental engineering.

In biomedical engineering, the research has broad focus areas. The first is biophotonics and biosensinghe is membrane transport and signaling. In first area, one group of faculty work on medical imaging techniques such as CT, tissue optics, OCT, photoacoustics, and ultrasoundgroup develop biosensing and bioimaging methodologies based on FRET, optical resonator, single-molecule sensing, and delayed fluorescence. In the second area, group focuses on cell electrophysiology and sensing including ion channels, Ca sensing, exocytosis, bioMEMS, and 2-photon microscopyrelated to neurological disorders.

Research in bioprocess engineering emphasizes bioresource utilization. Areas of research include biomass-based products (fuels, foams, and chemicals), food engineering, and bioprocess automation. In the bioenvironmental engineering area, the emphasis is on water quality issues, including wastewater treatment, bioremediation, precision chemical application technologies, and non-point source pollution.

Part of the BE core faculty are housed in the and the Dalton Cardiovascular Research Center. The affiliated faculty members are from five different colleges/schools on campus. Current externally-funded research exceeds $10M and research funding comes from major sources such as NIH, NSF, USDA, the Coulter Foundation, American Heart Association and industry, including three current NSF-CAREER Awards.

Chemical Engineering

Faculty and students in Mizzou’s Department of Chemical Engineering conduct research in three broad areas: biomedical innovation, sustainable energy technologies, and sustainable water cycles.

Civil and Environmental Engineering

Design and testing of steel bridges, non-destructive testing of bridges, retrofitting existing structures earthquake resistant design, explosion resistant design, nanotechnology and high-performance calculations, stability and performance of earth slopes, foundations, earth retention systems, unsaturated soils, soil dynamics, risk and reliability, geoenvironmental engineering, site remediation, bioremediation of soils and groundwater, intelligent transportation systems, traffic flow characteristics, bicycle and pedestrian transportation, highway design, applications of geographical information systems, remote sensing to civil engineering problems, drinking water quality, wastewater treatment, water reuse, membrane process, environmental nanotechnology, biodegradation and biotransformation, renewable energy from waste, hydrology, wetlands, water resources engineering, hydrological engineering, remote sensing, and stormwater management.

Computer Science

Research in the department covers a wide range of interests including computational biology and bioinformatics, medical informatics, large dataset scientific visualization, image processing, cyber-security, multimedia communications and networking, sensor network and nonlinear optimization, spoken language processing and human-machine interfaces, distributed computing, geospatial information mining and retrieval, etc. Our major research projects are heavily funded by both federal governments and industries. While National Science Foundation (NSF), National Institute of Health (NIH), National Geospatial-Intelligence Agency (NGA), Department of Energy (DoE), and Department of Defense (DoD) are examples for federal funding, Raytheon, Microsoft, and Monsanto are representatives for industrial funding.

Electrical & Computer Engineering

Nanotechnology, geospatial intelligence, MEMS, pulse power, eldercare and rehabilitation, computational intelligence, computational neurobiology, power electronics, power systems, telecommunication networking, remote sensing, robotics, video and image coding and compression, wireless communication, optoelectronic device design and fabrication, medical image compression and telemedicine, electromagnetic decontamination, electron accelerators and electron beam applications, digital power measurement, antenna design, bioelectrics.

Industrial & Manufacturing Systems Engineering

The Department of Industrial and Manufacturing Systems Engineering conducts advanced research investigating and improving the systems aspects of the service and manufacturing sectors. Within these application areas, the Department applies sets of tools to address a variety of problems. These tools include optimization methodologies, integration theory, static and dynamic systems modeling, and evaluation techniques.

Departmental research, however, is not only the application of tools to solve problems. It is also the development and refinement of the theories and the methodologies underlying these tool sets, resulting in new and improved methodologies. Therefore, Departmental research can be viewed from two perspectives: (1) the application area of the problem and (2) the tools and techniques developed to solve the problem.

Current research projects run the gamut from educational and curricular innovations to basic research. Examples of current research projects include the development and evolution of a collaborative course sequence on entrepreneurship and innovation; the application of theory of constraints to railroad routing and expansion; the reliability and quality assurance of state bridges; the study of economic emergence which deals with the impacts of entrepreneurship, social infrastructure, and data mining techniques for qualitative and quantitative data; the development of a design retrieval system based on associated memory; the development of strategic models for non-profit organizations to determine how to best "re-engineer" their processes; the study of supply chains and other logistical issues in service and manufacturing sectors; the reduction of errors in the health care sector; the systems analysis of the health care industry and ways to develop Healthcare Engineering; the study of systematic scheduling methodologies in complex and dynamic environments focusing on the development of efficient heuristics based on the exploration of structural properties, especially when jobs with stochastic processing times and deterministic due dates arrive randomly; development of a user-friendly graphics-based sawing trainer for hardwood sawyers that incorporates the ability to nondestructively evaluate outcomes of log sawing strategies on log specimens modeled from several log species; the combination of sensor technology and the information systems to food supply monitoring; development of new techniques, structural results, and approximations for dynamic process control in the presence of resource constraints and uncertainty; development of the underlying theory and tools necessary to cultivate Virtual Enterprises systems for strategic planning that is adaptable to any situation and that can be rapidly employed; development of models and solution techniques that integrate both "structural" and "operational" issues within a single approach to obtain better overall designs for material flow systems; development of the basic structure of interior point methodologies for integer programming applications; ergonomics related to hospital beds and nurse task fatigue; winter maintenance optimization for the state; optimization in radiation therapy; wireless sensor relocation; fictitious play in stochastic systems; and the development of models for highly variable enterprises such as farming and the consequences of this variability on the related supply/demand chains.

Mechanical and Aerospace Engineering

Enhanced electronic cooling, design and modeling of microheat pipes, nanofluid oscillating heat pipes, phase change phenomena, thermophysical behavior of nanofluids; nonequilibrium irreversible thermodynamics, high-rate small-scale heat transfer and the associated materials failure, dynamical theories of thermoelectricity; effective thermomechanical properties in micro-devices and composites, thermal and strain localization in high-speed penetration; nanomaterial fabrications, testing, and characterizations; low temperature plasma surface alternations; x-ray and neutron diffraction in composites and oscillating heat pipes, high-strength transparent composites; ultrasonic material characterizations; integrating computer aided manufacturing and expert systems, high-speed machining; orbital mechanics, trajectory optimization, optimal and robust control, guidance and control systems and optimization, modular design; computational design, analysis, and optimization, biomechanics and modeling of complicated systems; high-pressure compaction of materials/bio-fuel; computational structural mechanics, composite and smart structures, structural health monitoring, nonlinear finite elements and optimization, deployable structures, modern nonlinear dynamics and large deformation; ultrafast laser-material interactions, characterizations, and ultrafast coupling; fluid power transmission and energy recovery devices.

Nuclear Science & Engineering

1) Advanced nuclear fuels
2) Nuclear waste disposal
3) Nuclear fuel burn-up
4) Reactor safety
5) Radioactivity dispersion and control
6) Deposition of radon in lungs
7) Plasma devices
8) Wide band-gap materials
9) Specialized sensors
10) Quantum Fingerprinting
11) Wide Band-Gap device fabrication and applications
12) Single crystal diamond neutron detectors
13) Wide Band-Gap radiation detection
14) Purification of semiconductor bulk materials
15) Corrosion resistant materials for nuclear systems (Gen IV reactors, thermochemical cycles)
16) Very High Temperature Reactors (VHTR)
17) VHTR fuels and safety
18) Fission product transport experiments and modeling
19) Pebble Bed Reactor
20) Materials research
21) Graphite particle generation studies
22) Hydrogen storage
23) Advanced materials for GEN IV reactors
24) Radiopharmaceuticals and micro-imaging
25) Radiochemistry
26) Gold nanoparticles for cancer diagnostics
27) High temperature adsorption of fission products
28) Emissivity
29) Dust production from Triso Fuel
30) Nuclear Batteries and Direct Energy Conversion
31) Nuclear Driven Lasers
32) Neutron Detection, Spectroscopy and Dosimetry
33) Transport Theory
34) Aerosol Mechanics
35) Rarefied Gas Dynamics
36) Kinetic Theory of Gases
37) Modeling and Simulation
38) Reactor Physics
39) Reactor Thermal Hydarulics
40) Radiation Diagnostics
41) Radiation Therapy
42) Drug delivery
43) Particle Inhalation
44) Optimization problems in Radiation therapy
45) Advanced Quality Assurance techniques
46) Proton Radiation therapy
47) Small animal radiation therapy
48) Image Guided Radiation Therapy
49) Brachytherapy

Research Description By Engineering Research Center

Center for Business Development

The MU Extension Business Development Program (BDP) helps Missouri’s entrepreneurs succeed and promotes the economic development of the state of Missouri. It performs this vital service through a network of business counselors/specialists located throughout the state.

The BDP network includes the Missouri Small Business & Technology Development Centers (MO SBTDC), which assist entrepreneurs with management, marketing, finance and commercialization issues and helps researchers, innovators and technology-based firms develop cutting-edge products and services, often through the acquisition of SBIR and STTR government agency awards. The BDP also includes the Missouri Procurement Technical Assistance Centers (MO PTAC), which assist firms in selling products and services to local, state and federal government agencies. Other BDP initiatives include environmental assistance and workforce development.

Center for Computational Biology and Medicine

The center hosts a synergetic team of computational scientists and field researchers in biology and medicine. Our team leverages the nationally recognized expertise of University of Missouri researchers in College of Engineering, School of Medicine, Life Sciences Center, School of Nursing, and Interdisciplinary Plant Group. This diverse team has been addressing the research problems in bioinformatics and health informatics. Collectively, the affiliate faculty of the center published more than 120 referred journals in the field over the past five years and secured multi-million dollars of funding from the National Science Foundation, the National Institute of Health, U.S. Army, and industry. Computer tools and database resources have been recognized by the international and national communities, such as Science Magazine and Critical Assessment of Techniques for Protein Structure Prediction (CASP) Competition.

Center for Eldercare and Rehabilitation Technology

The center includes an interdisciplinary group of researchers who are focused on investigating, developing, and evaluating technology to serve the needs of older adults and others with physical and cognitive challenges. Current work is focused on monitoring older adults through a network of sensors ranging from simple motion sensors to video sensors to a bed sensor that captures sleep restlessness and pulse and respiration levels. Data collection has been ongoing for over four years, allowing researchers to study the data and develop algorithms for identifying alert conditions such as falls as well as extracting typical daily activity patterns for an individual.

Center for Geospatial Intelligence

The Center for Geospatial Intelligence (CGI) is an interdisciplinary center that involves faculty and researchers in Electrical Engineering, Computer Engineering, Computer Science, Geography, Civil & Environmental Engineering, and Geological Sciences. The center leverages significant ongoing R&D activities in the areas of satellite and airborne remote sensing, advanced geospatial data processing, automated feature extraction and target recognition, large dataset visualization, computer vision, intelligent databases, information retrieval, and the detection and characterization of underground structures. By leveraging these multi-disciplinary research skills, the center conducts leading-edge research focused on geospatial intelligence needs critical for national security, homeland defense, and military combat support.

Center for Micro/Nano Systems & Nanotechnology

The Center for Nano/Micro Systems and Nanotechnology uses micro/nano-facrication and nanotechnology to research and develop miniaturized systems. Many of these technologies can be used for both military and private purposes, such as the microchip-based shock wave generator that can set off explosive weapons as well as detect cancer. Another microchip-based technology under development can be used both to detect biological threats and to detect Human Immunodeficiency Virus (HIV) or cancer. The Center is also working on synthesizing nanostructured materials such as quantom dots, nanopores, nanoparticles, nanorods, and nanowires for life sciences, energy and defense applications. One of the applications of the quantum dots and nanoparticles is fabrication of memory devices. Memory devices can be fabricated using a dielectric material with ordered nanoparticles in the matrix which works as a charge center. The Center has developed a new coating technology that can be used as an electrical insulation for surgical tools. This coating is also good for fabricating high density capacitors. Another area of research is single cell detection. The Center developed a microdevice which is capable of detecting a single cell for further study. The Center successfully developed a nano material based imaging system where nano materials can be delivered inside the body with the help of shock waves and image it with the help of fluorescent materials which remain inside the nanoparticle. The Center is also developing a power generator based on nanocrystalline silicon carbide and a mechanically hard coating for various applications (abrasion resistant, wear resistant, hydrophobic, hydrophilic and antireflection coating).

Center for Thermal Management

Center focuses on high-power electronic devices for defense, life science and environmental applications. Defense-related programs include research into techniques for detection as well as directed energy weapon research. Other applications encompass the environmental and medical fields, including work on pulsed electric fields, pulsed UV and electron beams that can inactivate bacteria or purify water.

MU Informatics Institute

The Institute hosts research and Ph.D. training programs in bioinformatics (Engineering) and health informatics (Medicine). Our interdisciplinary research foci include structural bioinformatics, high-throughput sequencing, phenotype-genotype associations, text mining and understanding, genomics database mining, medical and molecular imaging informatics, and human computer interaction in health care. Our faculty developed many nationally and internationally recognized computational tools to streamline knowledge discovery process in the fields of agriculture, biology, cancer treatment, community medicine, and patient safety. Our ongoing researches are mainly funded by the National Science Foundation, the National Institute of Health, U.S. Army, the National Geospatial-Intelligence Agency, the National Institute of Justice, the National Center for Soybean (NCSB) Technology, and Missouri Soybean Merchandising Council.